Building a pipeline from the Nation's 1st Tribal College to the Neurosciences
Can the Alzheimer's Brain Regenerate and Recover?
Native Americans are among the most underrepresented groups in the biomedical sciences, accounting for just 0.5% of the total workforce, lower than any other racial or ethnic group, according to the National Institutes of Health.
Additionally, they face significant disparities in health care compared with other U.S. populations. Though more than a third of the most prevalent health disparities in Native American communities are related to brain health, the diagnosis, treatment and study of these disorders is complex. Meeting these multifaceted challenges requires the development of a biomedical workforce rooted in the traditions and cultures of Native American populations.
On Every Front: Developing a Diverse Scientific Workforce To End the Alzheimer’s Epidemic
The University of Arizona Center for Innovation in Brain Science has received a $37.5 million grant from the National Institutes of Health to research a potential regenerative therapy for Alzheimer's disease through a national multi-site Phase 2 clinical trial to determine the effectiveness of allopregnanalone, or allo, as a treatment for individuals with early-stage Alzheimer’s who carry the genetic risk factor for the disease.
A team led by Roberta Diaz Brinton, PhD, director of the Center for Innovation in Brain Science, received a $37.5 million dollar grant from the National Institute on Aging. The five-year grant will fund a national multi-site Phase 2 clinical trial to determine the effectiveness of allopregnanalone, or allo, as a treatment for individuals with early-stage Alzheimer’s who carry the genetic risk factor for the disease.
Why women? -- Studying the role of gender in Alzheimer's disease
Roberta Diaz Brinton, PhD, inaugural director of the Center for Innovation in Brain Science at the University of Arizona Health Sciences, has been awarded a $1.8 million National Institutes of Health training program grant to develop a cross-disciplinary and translationally oriented workforce to discover new drugs for Alzheimer’s and other neurodegenerative diseases and shepherd them through the drug-development pipeline.
UA chemical biologists unearth cause of a rare brain disorder
Roberta Diaz Brinton received a $5.9 million grant to study the role of gender in Alzheimer’s disease and develop precision medicine interventions to prevent — and potentially reverse — the course of the disease in women and men.
UA receives $10.3 million to help unlock the mystery of Alzheimer's in women
Babies born with pontocerebellar hypoplasia type Ib often do not survive past one year. Born with an underdeveloped brain, infants struggle to move, feed and even breathe. Scientists have little understanding about the biology behind the deadly disease besides knowing that a genetic mutation is implicated. Now, researchers at the University of Arizona College of Medicine - Tucson have keyed into the biological mishap that causes stunted brain growth and, ultimately, muscle movement failure.
5-year National Institute on Aging program project grant led by Roberta Diaz Brinton, Ph.D., inaugural director of the Center for Innovation in Brain Science at the University of Arizona Health Sciences